质量一般的布里格姆

2023年6月26日

由布莱根妇女医院的一项研究中,质量一般的布里格姆的创始成员卫生保健系统,揭示了大量的酚生物标志物的存在之间的联系,改变了女性寻求生殖治疗的甲状腺激素水平。他们的研究结果,发表在《毒物,揭示新的深入了解环境毒素和生活方式的决定可能影响生殖健康。ANI |更新:26-06-2023 21:28坚持|创建:26-06-2023 21:28是代表形象。图片来源:ANI:分享由布莱根妇女医院的一项研究中,质量一般的布里格姆的创始成员卫生保健系统,揭示了大量的酚生物标志物的存在之间的联系,改变了女性寻求生殖治疗的甲状腺激素水平。他们的研究结果,发表在《毒物,揭示新的深入了解环境毒素和生活方式的决定可能影响生殖健康。“很多女性现在甲状腺问题的经验。因此,我们旨在确定一些预测甲状腺激素水平,以帮助女性改善他们的健康,”资深作者莉迪亚•Minguez-Alarcon博士说,英里,哈佛医学院助理教授,布里格姆的生殖学家钱宁分工网络的联合调查者医学和环境和生殖健康(地球)的研究。”在这种情况下,一个女人的健康不仅仅是她的幸福,而且她的生育能力和知识的危险。”Repeated exposure to specific phenol chemicals found in everyday items like toys, sunscreen, dental products, food packaging, and food preservatives can disrupt hormonal balances within the body, leading to adverse health effects. Previous studies have evaluated these individual chemicals and their effects on the thyroid. However, the combined impact of these multiple phenols on the endocrine system, particularly in relation to female fertility, is not yet fully understood. Fertility relies crucially on maintaining a steady harmony of hormones within the body. Disruptions to these levels can occur from external sources, particularly exposure to environmental hazards. Brigham researchers sought to assess the impact of some of the most common environmental chemicals that have been shown in animal models to affect thyroid hormones. Their study looked at 339 women seeking care at a fertility clinic. The team evaluated urinary concentrations for phenol biomarkers and serum samples for molecular markers of thyroid function and thyroid autoimmunity. Various statistical methods were then used to gauge the combined influence of these biomarkers on thyroid levels. By evaluating the simultaneous combinations of chemicals, the researchers were able to more accurately capture real world effects as humans are exposed to hundreds of chemicals at the same time, not just one by one. The researchers observed that the presence of urinary bisphenol A, methylparaben and triclosan were also associated with altered thyroid hormonal levels, and some of them were suggestive of thyroid diseases, including hypothyroidism. All of these phenols can be found in consumer products, regulated by the United States Food and Drug Administration. The researchers acknowledged that some of their measured associations diverged from findings in previous publications. This could be due to different study populations, phenol biomarker concentrations, or other phenols that were not measured in this study. Future studies should repeat these tests and consider the long-term consequences of altered thyroid function. "This study is particularly unique in its focus on women whose fertility is sub-optimal, who have been shown to be at higher risk for thyroid disease," said Minguez-Alarcon. "In previous research with the same study cohort (EARTH), we found that women with altered thyroid hormones had lower ovarian reserve, measured as diminished antral follicle count. Thus, while more longitudinal studies will be needed to corroborate these results, preventing significant fluctuations in thyroid hormonal levels could be crucial for maintaining a women's fertility potential." (ANI) (This story has not been edited by Devdiscourse staff and is auto-generated from a syndicated feed.) Advertisement